Well, the only real way to protect yourself from "slow corruption" that was left unnoticed for some reason, is versioning. As an added benefit, it will also allow you to revert undesirable modifications consciously made to the data by the users.
If the data is very large, then you'd probably have to opt for finely granulated differential backups, i.e. differential backups that can detect and store only the modified portions of files. Of course, the problem with such backups is that they require more-or-less proprietary format for storing the backup data. SB does not support that, AFAIK.
As for "slow corruption of HD"... It is not like the OS is just reading some magnetic data from the HD platter without knowing whether it is good or bad. Any modern file system will detect the data corruption the moment it begins, since they store various checksums and such for the data read from the drive. This means that there will always be a way to catch the problem once the corruption begins. Monitoring your drive's SMART data can also help. There are quite a few tools out there that will do that for you, like free Acronis Drive Monitor utility for one example.
If the data is very large, then you'd probably have to opt for finely granulated differential backups, i.e. differential backups that can detect and store only the modified portions of files. Of course, the problem with such backups is that they require more-or-less proprietary format for storing the backup data. SB does not support that, AFAIK.
As for "slow corruption of HD"... It is not like the OS is just reading some magnetic data from the HD platter without knowing whether it is good or bad. Any modern file system will detect the data corruption the moment it begins, since they store various checksums and such for the data read from the drive. This means that there will always be a way to catch the problem once the corruption begins. Monitoring your drive's SMART data can also help. There are quite a few tools out there that will do that for you, like free Acronis Drive Monitor utility for one example.