You're using a variable that has been assigned a value that now doesn't match any drive on your system. You can edit the string with the new serial manually, of course ![Smile :)]()
But it would be quicker to edit it to use* the current drive letter, then click Alternatives and pick it from the list. Having done so, you can repeat that process for all profiles that need it, or Copy/Paste the new serial from profile #1 to profile #2/3/4...
There's no way to centrally edit it, because it's not stored centrally. It's stored per-profile. It's the same concept as if you used UNC paths and for some reason changed a server (or its machine-name). You'd need to edit the UNC paths in the individual profiles to match.
* Note: you can't work backwards (using our code) to switch to the drive letter of the old drive based on cross-matching the serial currently in the string, precisely because that serial isn't present on the system now to cross-reference anyway

But it would be quicker to edit it to use* the current drive letter, then click Alternatives and pick it from the list. Having done so, you can repeat that process for all profiles that need it, or Copy/Paste the new serial from profile #1 to profile #2/3/4...
There's no way to centrally edit it, because it's not stored centrally. It's stored per-profile. It's the same concept as if you used UNC paths and for some reason changed a server (or its machine-name). You'd need to edit the UNC paths in the individual profiles to match.
* Note: you can't work backwards (using our code) to switch to the drive letter of the old drive based on cross-matching the serial currently in the string, precisely because that serial isn't present on the system now to cross-reference anyway